Gynaecology Research Today is a free monthly online journal that collates and summarizes the latest research about Gynaecology, including details on pap smears, laparoscopy, ultrasound, hysteroscopy.

A study to establish gestation-specific reference intervals for thyroid function tests in normal singleton pregnancy.

Cotzias C, Wong SJ, Taylor E, Seed P, Girling J

West Middlesex University Hospital, Twickenham Road, Isleworth, Middlesex TW7 6AF, England, United Kingdom. christina.cotzias@wmuh.nhs.uk

OBJECTIVE: To establish gestation-specific reference intervals for thyroid function tests in normal singleton pregnancy. STUDY DESIGN: Cross-sectional observational study performed in the Obstetric and Gynaecology department, West Middlesex University Hospital. A single blood sample from 335 pregnant women at various gestations of pregnancy was analysed for thyroid function. FT4, fT3, TSH values at each gestation of pregnancy were calculated. RESULTS: From the fT3, fT4 and TSH results, a 95% reference interval was calculated for each hormone for each week of pregnancy. CONCLUSION: We calculated gestation-specific reference intervals for thyroid function tests throughout pregnancy to facilitate clinical management of thyroid disease in pregnancy.

Published 25 February 2008 in Eur J Obstet Gynecol Reprod Biol, 137(1): 61-6.
Full-text of this article is available online (may require subscription).

© 2005-2008 Gynaecology Research Today. All Rights Reserved.