Gynaecology Research - Pap Smears, Laparoscopy, Ultrasound, Hysteroscopy

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Reasons for early interventions by gynaecologists in a clinical follow-up study on cervical intraepithelial neoplasia.

Tiersma ES, Peters AA, van der Lee ML, Visser AP, Fleuren GJ

Bakhuis RoozenBoomstratt 36, Gynaecology and Obstetrics, 2313 RD Leiden, The Netherlands. emtiersma@yahoo.com

OBJECTIVE: In a previous clinical follow-up study on psychosocial factors and cervical intraepithelial neoplasia (CIN), we had noticed a high percentage of early interventions to the cervix by gynaecologists, in discordance with the research protocol. The aim of the current study was to investigate the reasons for these interventions. STUDY DESIGN: We retrospectively analysed the study records of the clinical study, concerning the follow-up of 98 patients with a CIN 1 or 2 lesion for 2.25 years by colposcopy and cervical smears. We recorded the number of early interventions that had occurred in the clinical study as well as the reasons for these interventions. A distinction was made between acceptable and unacceptable reasons for early intervention. RESULTS: During follow-up, 39 out of 98 women (40%) had undergone intervention in discordance with the protocol. No acceptable reason for these interventions was found for 67% of these patients (26/39). In the majority of these cases either no reason for the intervention had been given, or the gynaecologist had feared for progression of the CIN lesion. CONCLUSION: Gynaecologists tend to intervene during follow-up of CIN, partly out of fear for progression. This tendency may complicate follow-up studies on CIN.

Published 30 April 2007 in Eur J Obstet Gynecol Reprod Biol, 132(1): 111-5.
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Gynaecology Research Today Archive:

Volume 1 (2005)
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