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Topical use of tranexamic acid to control perioperative local bleeding in gynaecology patients with clotting disorders: two cases.

Sarris I, Arafa A, Konaris L, Kadir RA

Royal Free Hospital NHS Trust, Department of Obstetrics and Gynaecology, London, UK.

Operating on patients with abnormal coagulation is a challenge frequently faced by surgeons. Achieving haemostasis perioperatively can involve bleeding points that would not ordinarily present a problem with intact clotting function. Here we present two women with localised wound bleeding following a gynaecological surgery in the presence of a clotting disorder. Haemostasis was successfully achieved with tropical use of tranexamic acid. These two cases illustrate a novel use for this antifibrinolytic agent. We suggest that there is a role for topical use of tranexamic acid in perioperative haemostasis in patients with clotting disorders.

Published 10 January 2007 in Haemophilia, 13(1): 115-6.
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