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The mean platelet volume in gestational diabetes.

Bozkurt N, Yilmaz E, Biri A, Taner Z, Himmetoğlu O

Department of Gynecology and Obstetrics, Faculty of Medicine, Gazi University, Turkey. nmbozkurt@yahoo.com

OBJECTIVE: To compare the platelet count and mean platelet volume (MPV) values of pregnancies diagnosed with gestational diabetes with those of healthy pregnancies. MATERIAL-METHOD: Between June 2003 and September 2004, 100 healthy pregnancies and 100 pregnancies with gestational diabetes were studied at Gazi University, Department of Obstetrics and Gynecology. RESULTS: While no statistically significant difference was observed in the platelet count between the two groups, the MPV of the gestational diabetes group (9.4 +/- 1.6 fl) was evaluated to be significantly higher than the MPV of the healthy pregnancy group (8.3 +/- 1.1 fl). Additionally, when linear regression analysis was performed an inverse relationship was observed between platelet number and MPV. CONCLUSION: There is a need for further research focusing on the platelet function in the observation and treatment of gestational diabetes, which can pose the risk of developing Type 2 diabetes for the mother and has negative consequences for the fetus.

Published 20 June 2006 in J Thromb Thrombolysis, 22(1): 51-4.
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